IKNL distinguishes the following research domains. The Netherlands Cancer Registry offers many opportunities for clinical and epidemiological research. In addition, together with Tilburg University,  IKNL established the PROFILES registry (Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship), that combines population-based cancer registry data with patient-reported outcomes. Patients can be monitored, also after treatment has ended, based on information they provide through questionnaires, leading to valuable insights into the long term consequences of cancer.

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