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Symposium: The Netherlands Cancer Registry in Europe Last November 30th the Netherlands Comprehensive Cancer Organisation hosted the online symposium of the Netherlands Cancer Registry. The symposium focused on how to improve cancer care and prevention with insights from cancer registries. Cancer registries are the fuel for Europe’s Beating Cancer plan. The registries provide insights to improve oncological care and prevention. The Netherlands Cancer Registry (NCR) is the national registration since 1989, maintained by the Netherlands Comprehensive Cancer Organisation (IKNL). The main goal is to reduce the impact of cancer, from the personal to the societal level. Together with care professionals, researchers, patients, and policy makers IKNL translates data into valuable insights. What lies ahead in the upcoming years and how can the cancer registries help to guide the way? The recording of the symposium can be found below. iknl.nl/en/news/symposium-the-netherlands-cancer-registry-in-e-(1) Laatst gewijzigd op: 30 november 2021

Cancer registries as fuel and engine for data driven rapid learning health systems, an interview with dr. Xander Verbeek In the Dutch session at HIMSS2021 dr. Xander Verbeek, head Research & Development at the Netherlands Comprehensive Cancer Organization was invited to share his vision on data analytics in oncology. He emphasized the role of the cancer registrations as fuel and engine for data driven rapid health systems, with the overall aim to learn from patients and improve health care. What is his vision for the future of data and AI to improve quality of cancer care? iknl.nl/en/news/cancer-registries-as-fuel-and-engine-for-data-driv Laatst gewijzigd op: 31 mei 2021

LANCELOT: new collaboration between IKNL and TNO to enable privacy preserving analyses on cancer-related data. The LANCELOT project is part of an ongoing strategic collaboration between the Netherlands Comprehensive Cancer Organisation (IKNL) and TNO, together with Janssen Pharmaceutica NV, to develop data infrastructure and AI solutions to enable the use of sensitive health data. LANCELOT will help to reduce the impact of cancer while preserving patients’ privacy. LANCELOT focuses on problems where the data of patients are spread across different organizations, for example at the General Practitioner, the hospital and the pharmacy databases. We are looking for additional partners in healthcare, to bring our solutions to the next level by performing pilot studies, embedding the solutions within legal agreements, and using data in a privacy-preserving manner. iknl.nl/en/news/lancelot-new-collaboration-between-iknl-and-tno-to Laatst gewijzigd op: 19 november 2021

Fewer breast and colorectal cancer diagnoses due to the COVID-19 crisis in the Netherlands Fewer breast and colorectal cancer diagnoses have been made in the Netherlands due to the COVID-19 crisis this spring. The decline in the number of diagnoses was more abundant in age groups invited to national population screening programmes, as compared to other age groups. More specifically, there was a drop of approximately one-third in breast cancer diagnoses (including its precursor) among 50-74-year-old women and approximately one-fifth in colorectal cancer diagnoses among 55-75-year-old men and women. These are the age groups that are invited to national population screening programmes in the Netherlands. Avinash Dinmohamed, Sabine Siesling, and coauthors described these findings in the Journal of Hematology & Oncology based on data from the Netherlands Cancer Registry (NCR) that relies on pathological cancer notifications via the Nationwide Histopathology and Cytopathology Data Network and Archive (PALGA). iknl.nl/en/news/fewer-breast-and-colorectal-cancer-diagnoses-due-t Laatst gewijzigd op: 6 november 2020

European collaboration in FLORENCE project Using AI to improve treatment of patients with colorectal cancer One in four patients in Denmark experience complications after colon cancer surgery, leading to re-admission, permanent damage and, in some cases, early death. A new research project, called FLORENCE, aims to improve the diagnosis, prognosis and treatment of patients with colon cancer. The project will develop an artificial intelligence (AI) tool to give doctors a better basis for decisions on patient treatment. iknl.nl/en/news/florence Laatst gewijzigd op: 22 juni 2023

NKR Online NKR Online biedt ziekenhuizen en regionale oncologienetwerken inzicht in het aantal diagnoses en behandelingen op ziekenhuis, regionaal en landelijk niveau, inzicht in de uitkomsten van behandelingen en inzicht in verwijzingen naar buiten de regio. Hiermee bieden we informatie ter ondersteuning van beleid. iknl.nl/nkr/cijfers-op-maat/nkr-online Laatst gewijzigd op: 3 januari 2021

ALERTNESS; structural signaling for up-to-date guidelines With financial support of ZonMw, IKNL partnered with the Dutch Association of Obstetrics and Gynecology (NVOG), Olijf Foundation and National Comprehensive Cancer Network® (NCCN®) to start the project ALERTNESS. The aim of the ALERTNESS project is to identify new developments in science and clinical practice to support timely guideline revision. Endometrial (uterine) cancer is the most common gynecological cancer in Western countries. In the Netherlands, about 1,900 new cases are diagnosed every year. All women with endometrial cancer are discussed in a multidisciplinary meeting and, if necessary, sent to one of the eight gynecological-oncology centers in their region. For optimal quality of care, it is important to treat these women according to the latest insights. Partly because several successive (gynecological) care providers are involved, an up-to-date and accessible guideline is crucial to ensure that every patient receives the right care in the right place. iknl.nl/en/guidelines/alertness;-structural-signaling-for-up-to-date-gui Laatst gewijzigd op: 8 september 2022

Changes to primary endpoints in immunotherapy trials: common and untransparent Nearly two-thirds of 38 examined randomized trials of immunotherapy in bladder, lung and kidney cancer included adjustment to primary endpoints. Only a minority of these studies reported these changes transparently, contrary to current guidelines. These are the outcomes of a review published by the Netherlands Comprehensive Cancer Organisation (IKNL), Radboud University Medical Center (The Netherlands), and Queens University Cancer Research Institute (Canada). iknl.nl/en/news/changes-primary-endpoints-trials Laatst gewijzigd op: 21 juni 2023

The need for gender medicine in oncology: ‘unexploited potential for individualised treatment’ n oncology, not much attention has been paid to the role of gender and sex. This is a missed opportunity to learn and individualise treatment, according to dr. Anna Dorothea Wagner, medical oncologist in the Centre Hospitalier Universitaire Vaudois in Lausanne and chair of the ESMO Gender Medicine Task Force. ‘Gender has so far rarely been included as an influencing factor in cancer research, although for instance in the field of cardiology it is clear that sex and gender play a role in the development and progression of disease.’ Wagner is working with researchers at IKNL to investigate the role of gender in non-sex related cancers, using data from the Netherlands Cancer Registry (NCR). iknl.nl/en/news/the-need-for-gender-medicine-in-oncology-unexploi Laatst gewijzigd op: 11 mei 2022

Cancer risk and survival in Europe depending on where your cradle is located Cancer is a major public health problem in Europe. In 2022, there were an estimated 2.78 million new cases of cancer in the 27 member states of the European Union (EU27) plus Iceland and Norway (EU+2 countries), equivalent to about five new diagnoses every minute. Cancer is expected to be the leading cause of death in Europe by 2035. The disparities in Europe are great and we need to address these disparities at the European level. That is the message of the newly released report Beating Cancer Inequalities in the EU: Spotlight on cancer prevention and early detection by the European Cancer Inequalities Registry (ECIR) and OECD (Organization for Economic Co-operation and Development). iknl.nl/en/news/beating-cancer-inequalities-in-eu Laatst gewijzigd op: 16 februari 2024

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